3T Biosciences is solving a major bottleneck in the field of immunotherapy – identifying novel targets that can be used to generate therapies to treat cancer in broad patient populations. We are developing transformative T cell receptor directed bispecific T cell engagers for cancer and other immune-related diseases. Our proprietary experimental and computational technology allows us to identify novel T cell receptor targets as well as clinical toxicities to develop safe and effective therapies.
We’re committed to making a difference for patients. Our ambitious, creative, and collaborative team makes 3T Biosciences the perfect engine to drive therapeutic solutions to reality. We’re looking for enthusiastic and self-motivated team-players to bring their talents to a fast-paced environment.
Typical Responsibilities:
- Lead and individually contribute to a data science team focusing on research, preclinical, and translational sciences
- Research areas: novel target discovery, immune repertoire analysis, machine-learning algorithms for protein-protein interactions through sequence-based data to assess TCR specificity/cross-reactivity
- Preclinical: Aid in the development of T cell engaging TCR mimic bispecifics towards novel targets through sequence-structure-function analyses
- Translational: Correlating patient responses based on patient and target biology
- Manage and develop internal workflows using multiple tools including AWS cloud-compute, version control in Git, and code repositories in Github
- Manage external collaborations focusing on target discovery
- Work cross-functionally with immunology and protein sciences/engineering teams
- Prepare and present updates on scientific findings to major stakeholders
Required Qualifications:
- Master’s (with 10+ years of industry experience) or PhD degree (with 4+ years of industry experience) in Bioinformatics, Computational Biology or quantitative field with management experience
- Experience in computational research, preclinical, and/or translational science supporting drug discovery programs, preferably in immuno-oncology
- Proficiency in multiple programming languages (e.g. R, python, command-line)
- Experience in machine-learned based tools for sequence and protein structure analysis
- Experience in dataset curation, integration, and management, ensuring reproducibility and data integrity
- Experience working with public biological databases (e.g., Ensembl, NCBI, UniProt, GEO, TCGA, IEDB)
- Proven ability to lead cross-functional teams, drive strategic initiatives, and foster a high-performance culture through clear communication, accountability, and collaborative leadership
- Strong written and verbal communication skills, with the ability to present complex scientific findings clearly to both technical and non-technical audiences
Please contact [email protected] with your cover letter and resume.
The annual salary range for this position is $215,000 USD to $245,000 USD. This salary range is an estimate of what we reasonably expect to pay for this posted position and the actual salary may vary based on various factors, including without limitation individual education, experience, tenure, skills and abilities, as well as internal equity and alignment with market data. This position is also eligible for annual performance bonus, benefits, paid time off and participation in company stock options.
3T Biosciences is an Equal Opportunity Employer and prohibits discrimination and harassment of any kind. 3T is committed to the principle of equal employment opportunity for all employees and does not discriminate on the basis of race, religion, color, sex, gender identify, sexual orientation, age, non-disqualifying physical or mental disability, national origin, veteran status or any other legally protected status.
