Publications

Tuning T cell receptor sensitivity through catch bond engineering
Science

Facile repurposing of peptide–MHC-restricted antibodies for cancer immunotherapy
Nature Biotechnology

Antigen Identification for Orphan T Cell Receptors Expressed on Tumor-Infiltrating Lymphocytes
Cell

Facile method for screening clinical T cell receptors for off-target peptide-HLA reactivity
BioRxiv

Stress-testing the relationship between T cell receptor/peptide-MHC affinity and cross-reactivity using peptide velcro
Proceedings of the National Academy of Sciences (PNAS)

T cell receptor cross-reactivity expanded by dramatic peptide/MHC adaptability
Nature Chemical Biology

Isolation of a Structural Mechanism for Uncoupling T Cell Receptor Signaling from Peptide-MHC Binding
Cell

Structural interplay between germline and adaptive recognition determines TCR-peptide-MHC cross-reactivity
Nature Immunology

Deconstructing the peptide-MHC specificity of T cell recognition
Cell

Discovery of surrogate agonists for visceral fat Treg cells that modulate metabolic indices in vivo
eLife

Autoimmunity-associated T cell receptors recognize HLA-B*27-bound peptides
Nature

Diversity-oriented approaches for interrogating T-cell receptor repertoire, ligand recognition, and function
Immunological Reviews

Opposing T cell Responses in Experimental Autoimmune Encephalomyelitis
Nature

Next-generation cancer therapies based on T cell receptors
Research Features

Antigen Identification for Orphan T Cell Receptors Expressed on Tumor-Infiltrating Lymphocytes
Cell

Identification of Antigenic Targets
Cell Cancer Trends

Intracellular targets as source for cleaner targets for the treatment of solid tumors
Biochemical Pharmacology

Interrogating the recognition landscape of a conserved HIV-specific TCR reveals distinct bacterial peptide cross-reactivity
eLife