3T Biosciences is solving a major bottleneck in the field of immunotherapy – identifying novel targets that can be used to generate therapies to treat cancer in broad patient populations. We are developing transformative T cell receptor directed bispecific T cell engagers for cancer and other immune-related diseases. Our proprietary experimental and computational technology allows us to identify novel T cell receptor targets as well as clinical toxicities to develop safe and effective therapies.
We’re committed to making a difference for patients. Our ambitious, creative, and collaborative team makes 3T Biosciences the perfect engine to drive therapeutic solutions to reality. We’re looking for enthusiastic and self-motivated team-players to bring their talents to a fast-paced environment.
About the Role
We are seeking Research Associate with experience in cell biology or immunology for a 6-month temporary contract role. This position will contribute to in vitro studies of bispecific T cell engagers for solid tumor indications and support projects for IND-enabling and translational studies. As part of our small, dynamic team, you will have the opportunity to gain broad exposure and contribute to multiple facets of the drug development process.
About You
You are a self-motivated, organized, detail-oriented, and inquisitive scientist who is driven by a desire to advance new medicines for patients. You hold high standards of scientific rigor for yourself and your colleagues and apply this rigor to achieve program and company goals. You are a team player who contributes to a positive and supportive working environment.
Typical Responsibilities:
- Perform in vitro immunological assays (e.g., cytokine release, cytotoxicity, flow cytometry) using primary immune cells and tumor cell co-cultures.
- Assist with in vivo efficacy and PK studies.
- Contribute to experimental design and analysis and support multi-disciplinary project teams.
Required Qualifications:
- Bachelor’s degree in biology or related field with 2+ years of work experience in industry or academic setting.
- Proficiency in immunology and in vitro methods for studying primary immune cells, especially in the context of immune oncology. Relevant techniques: MSD or ELISA, Incucyte or similar, flow cytometry and FACS, and other platereader-based functional assays (e.g. LDH release).
- Proficiency in aseptic technique for the routine culture, maintenance, expansion, and cryopreservation of various mammalian cell lines.
- Strong organizational skills as demonstrated by an ability to advance multiple experiments at the same time in addition to clear and detailed recordkeeping, e.g. electronic lab notebook entries and experiment reports
Preferred Qualifications:
- Proficiency in isolating, culturing, and activating primary human immune cells for use in downstream functional assays
- Experience in animal handling including dosing techniques and blood collection. Experience with xenograft tumor models a plus
- Experience with Benchling.
Please contact [email protected] with your cover letter and resume.
This position is an hourly contract position and will be staffed via a temporary employment agency. Temporary employment agency will serve as employer, process all payroll, withhold taxes, and carry workers’ compensation insurance for Worker. This position is not eligible for annual performance bonus, benefits, paid time off or participation in company stock options.
3T Biosciences is an Equal Opportunity Employer and prohibits discrimination and harassment of any kind. 3T is committed to the principle of equal employment opportunity for all employees and does not discriminate on the basis of race, religion, color, sex, gender identify, sexual orientation, age, non-disqualifying physical or mental disability, national origin, veteran status or any other legally protected status.
