Position Specifics:

3T Biosciences is an industry leader in TCR targeting and therapeutics discovery for the treatment of solid tumors and solving a major bottleneck in the field of immunotherapy – identifying novel targets. 3T’s novel 3T-TRACE platform is designed to overcome the challenges of advancing TCR-based therapeutics. We are developing transformative T cell receptor therapies for cancer and other immune-related diseases. Our proprietary experimental and computational technology allows us to identify novel T cell receptor targets as well as clinical toxicities to bring safe and effective therapies to patients in need of new treatment options. 

Culture:

We’re committed to making a difference for patients. To be successful as a team member, you should demonstrate passion and dedication. Our innovative, creative, and ambitious team makes 3T Biosciences the perfect engine to drive therapeutic solutions to reality. We’re looking for enthusiastic and self-motivated individuals to bring their talents to a fast-paced environment.

Your Typical Responsibilities:

  • Key contributor to the pharmacology team, with broad responsibility to identify and characterize drug candidates in our pipeline
  • Duties include planning, management and analysis of in vivo PK and pharmacology studies at CROs.
  • Design of tumor organoid pharmacology studies to test therapeutic compounds for antitumor activities in collaboration with academic collaborators or CROs
  • Collaborate on multiple projects and work closely with scientists from cross-functional disciplines to design studies and meet project deliverables in a timely manner
  • Contribute to scientific manuscripts, patent applications, and regulatory documents
  • Organize and present summaries of results and ideas at internal and external meetings.
  • Maintain a working understanding of projects and relevant literature to conduct experimental work to support team goals
  • Maintain up to date knowledge of advancements in the field and new laboratory techniques and technologies
  • Maintain accurate, well-organized experimental records

Required Qualifications:

  • PhD with 3+ years, or BS or MS with 5+ years relevant industry experience
  • A strong background in immunology, tumor immunology and T cell biology
  • Expertise to design and execute in vitro assays to support evaluation of therapeutics
  • Expertise using biologics in preclinical in vivo oncology models, specifically immune reconstituted models, including design of xenograft tumor studies, tumor measurements, drug administration, tissue processing and data analysis
  • Experience with PK/PD studies and a working understanding of the tumor microenvironment in xenograft tumor models.
  • Working knowledge of pharmacodynamic analysis of tumors and immunohistochemistry
  • Experience in the phenotypic and functional characterization of immune cell populations in tumors and other organs.
  • Ability to function independently, as well as work closely in cross-functional teams to support multiple pre-clinical stage programs
  • Ability to clearly and efficiently document, communicate and present complex data sets
  • Ability to function in a fast-paced, team-based work environment, and manage competing priorities or projects and meet deadlines

Preferred Qualifications:

  • Experience with testing cell therapies in vivo and/or monitoring primate studies desirable
  • Experience with analytical techniques including multicolor flow cytometry, ELISA, cytotoxicity and proliferation assays
  • Experience with Asana and Benchling for project tracking/management
  • Experience with MSD and related platforms

Please contact recruiting@3tbiosciences.com with your cover letter and resume and reference Req# 200-01.


3T Biosciences is an equal opportunity employer. We proudly celebrate diversity and are dedicated to inclusivity.

3T Biosciences does not accept profiles, candidate summaries, or resumes from recruiting vendors without a binding written agreement. Any unsolicited submission of services and or resumes in no way creates an obligation or duty by 3T Biosciences, implied or otherwise.