Position Specifics:

Research Associate/ Senior Research Associate– Therapeutic Discovery (T Cell Engineering)

3T Biosciences is solving a major bottleneck in the field of immunotherapy – identifying novel targets that can be used to generate therapies to treat cancer in broad patient populations. We are developing transformative T cell receptor therapies for cancer and other immune-related diseases. Our proprietary experimental and computational technology allows us to identify novel T cell receptor targets as well as clinical toxicities to bring safe and effective therapies.


We’re committed to making a difference for patients. Our focused, creative, and ambitious team makes 3T Biosciences the perfect engine to drive therapeutic solutions to reality. We’re looking for enthusiastic and self-motivated individuals to bring their talents to a fast-paced environment.

Your Typical Responsibilities:

  • Engineering primary T cells or T cell lines with lentivirus and/or CRISPR/Cas9
  • Performing assays to measure T cell activation and target cell killing (flow cytometry, live cell imaging, plate reader)
  • Mammalian cell culture and media preparation
  • Interfacing with a team of computational and experimental biologists to aid in experimental and computational designs

Required Qualifications:

  • Bachelors with 2+ years experience relevant to primary immune cell research (title commensurate with experience)
  • Extensive experience with mammalian cell culture
  • Experience with one or more of the following cellular immunology techniques: flow cytometry, cytokine secretion assays, T cell activation assays, cell killing assays
  • Experience with basic molecular biology (cloning, plasmid preparation, PCR, etc.)
  • Self-motivated and a proactive thinker – can work independently and in teams
  • Excellent written and communication skills presenting scientific data

Preferred Qualifications:

  • 2+ years industry experience
  • Experience working with primary human blood cells (e.g. isolating PBMC, performing assays with primary T cells, etc.)
  • Knowledge and/or experience with lentivirus transduction or CRISPR/Cas9 genome editing
  • Knowledge and/or experience with adoptive T cell therapies
  • Experience using Benchling and Asana

Please contact john.leonard@3tbiosciences.com with your cover letter and resume.

Please contact info@3tbiosciences.com with your cover letter and resume.